Nonsteroidal Anti-inflammatory Drug-related Gastrointestinal Bleeding in the Elderly
Nonsteroidal anti-inflammatory drug (NSAID) could induce gastrointestinal (GI) injury by way of topical (mucus, gastric acid and drug interaction) and systemic mechanism (decreased prostaglandin synthesis).Compared with non-NSAID users, elderly taking NSAID or aspirin have a higher chance than younger people of developing GI bleeding (5.5-fold vs.1